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These results shed light on the role that GIP receptor agonism plays in the therapeutic profile of dual receptor agonism and provide mechanistic explanations for the clinical effectiveness of tirzepatide [80]
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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as highly effective therapies for weight reduction and glycemic control, and they show promise in improving fertility outcomes in women with obesity and PCOS [5,6]
doi: 10.1172/JCI24335
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