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Description
A 53% share of the international GLP-1 market
It has also been suggested that brain penetrance differs between different GLP-1 analogs, with nonacylated and non-PEGylated analogs like exendin-4 or lixisenatide showing significant rates of brain influx, while liraglutide or semaglutide do not have reliable BBB crossing (143), at least in male mice

Am J Clin Nutr 102(1):115122 Demay MB, Pittas AG, Bikle DD, Diab DL, Kiely ME, Lazaretti-Castro M et al (2024) Vitamin D for the prevention of disease: an endocrine society clinical practice guideline

Worldwide trends in underweight and obesity from 1990 to 2022

For cagrilintide, injection site reactions are slightly more common than with most peptides

[(accessed on 7 January 2026)];2022 Available online: 83.Eli Lilly Company Zepbound (Tirzepatide) Injection for Subcutaneous Use, U.S