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To investigate whether this partial effect was due to an incomplete knockdown, we performed experiments in HEK293 cells with both -arrestin isoforms deleted by CRISPR-Cas9 41

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Okatani, Y., Okamoto, K., Hayashi, K., Wakatsuki, A., Tamura, S., & Sagara, Y

& Dekkers, O

[35] reported that a 6-month exenatide-based therapy produced a 42% relative reduction in intrahepatic lipid content, accompanied by a mean BW loss of 5 kg and significant decreases in both abdominal subcutaneous and visceral fat volumes

Further studies are warranted to elucidate the effects of liraglutide on adipocytokines and LFC
