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Besides biological explanations, social factors like better adherence or a stronger motivation to lose weight among women might explain some of the differences

[DOI] [PubMed] [Google Scholar] 21.Popovic DS, Patoulias D, Popovic LS, Karakasis P, Papanas N, Mantzoros CS

If BMI 18.5 kg/m 2 is reached at any time during the treatment period, or the participant has significant gastrointestinal symptoms despite management, the investigator will be advised to contact the sponsor medical monitor to discuss whether continuing the study treatment is medically appropriate

and reducing stellate cell activation, potentially reducing their fibrotic response to liver injury [37]

Sterne JAC, Savovi J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al

JAMA (2023)
