glp 1 drugs for rheumatoid arthritis GLP-1 Medications and Arthritis: What the 2025 Research Actually Shows Could this treatment END Rheumatoid

IDF Diabetes Atlas, 8th edn., 2017

This study was completed by two teams that worked independently, each composed of a clinician and research scientists

GLP-1 is a multifaceted hormone, and the use of its analogs is associated with broad metabolic effects: they increase insulin secretion, decrease glucagon release, increase glucose uptake in muscles, decrease glucose production in the liver, improve lipid profile, slow gastric emptying, and increase satiety leading to weight loss (40)

Herring recommends working with clinicians to explore other medications or non-drug interventions

Here are the most common GLP-1 drugs: Semaglutide (Ozempic, Rybelsus) Exenatide (Byetta, Bydureon) Liraglutide (Victoza, Saxenda) Dulaglutide (Trulicity) Lixisenatide (Adlyxin) Albiglutide (withdrawn from the market) Exenatide Extended-Release (Bydureon) Efpeglenatide (Lyxumia, ZYOG1) Out of all, the most popular is Semaglutide

Some meta-analyses show small reductions in body weight (0.5-1 kg) and improvements in fasting glucose, while others show no significant effect