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Setting: Random sample of 16 million patients (2006-2020) from the PharMetrics Plus database (IQVIA), which is a large health claims database of outpatient prescriptions and International Classification of Diseases 9 th and 10 th Edition ( ICD-9/ICD-10 ) diagnoses

Additional file 1: Fig S11), Sleep apnoea syndrome (RR 0.81, 95% CI 0.481.36, p = 0.43

In contrast, Ozempic and Wegovy primarily work by dulling appetite, with less emphasis on broader metabolic resilience

Drink Plenty of Water Fiber needs water to do its job

Key benefit: Proven to result in significant weight loss with minimal lifestyle disruption