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Each subject received in a random order a single subcutaneous dose of 1.2 mg liraglutide and placebo at an interval of 48 h, with subsequent clinical follow-up in the metabolic ward, during which blood pressure was monitored for the following 24-h and 24 h urinary samples were collected to assess sodium excretion

Red flags requiring prompt evaluation include heavy or irregular bleeding, pelvic pain, galactorrhea, signs of androgen excess, or missed periods with negative pregnancy tests

doi: 10.1007/s13300-025-01784-x [DOI] [PMC free article] [PubMed] [Google Scholar] 205.Packer M, Zile MR, Kramer CM, et al

Coordinating with a primary care physician or endocrinologist

2017;2(14):e93751

These results demonstrate that tirzepatide's dual mechanism typically outperforms semaglutide, even when tirzepatide doses are numerically lower
