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Metformin and gut microbiota: their interactions and their impact on diabetes

Furthermore, GLP-1 agonists preserve mitochondrial integrity, reduce endoplasmic reticulum stress, and inhibit cardiomyocyte apoptosis through activation of the PI3K/Akt and AMPK pathways [82]

However, a clinical study from 2022 reported that hair loss (alopecia) occurred in 4.9% to 5.7% of people using a 5 mg to 15 mg dose of Mounjaro, compared to 0.9% of those using the placebo

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Endocrinology 142: 45224528, 2001

[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Han J.E., Frasnelli J., Zeighami Y., Larcher K., Boyle J., McConnell T., Malik S., Jones-Gotman M., Dagher A