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This scenario leads to an increase in oxidative stress (OS), which is related to mitochondrial dysfunction, accumulations of protein and oxidated lipids, and an impairment of the antioxidant system [64,65,66,67,68,69,70]

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In its therapeutic form, GLP-1 receptor agonists mimic this hormone, offering a powerful approach to weight loss

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their association with SGLT-2 inhibitors requires further confirmation through large, randomized trials ( SGLT2 inhibitors should be discontinued in specific clinical scenarios to mitigate potential adverse events

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