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Constipation occurs in some individuals due to slowed gastrointestinal transit, while others may experience loose stools or diarrhea

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Zepbound vomiting and diarrhea together are uncommon but happen most often during dose-escalation weeks or after a high-fat meal close to an injection

Empagliflozin is not recommended for patients with severe renal impairment, end-stage renal disease, or those receiving dialysis because its effectiveness relies on the kidneys' ability to filter glucose from the blood