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After 8 weeks of follow-up, the administration of lixisenatide increased the phosphorylation of NHE3, which reduced its activity in urinary extracellular vesicles in comparison to once-daily insulin glulisine treatment (Tonneijck et al., 2019)

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Pregnancy and PCOS Because PCOS raises your risk of diabetes and high blood pressure, once you get pregnant, you may be at increased risk for gestational diabetes and pre-eclampsia

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These agents have now been in patients for decades without major safety signals but as with any agent, further vigilance is required

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[DOI] [PubMed] [Google Scholar] 320.Lim G.E., Brubaker P.L

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