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At 28 weeks (roughly 6.5 months), average weight loss reaches approximately 12 to 14%

Additionally, these studies noted an acute dip in eGFR with SGLT2i, suggesting a therapeutic reduction in glomerular hypertension

Heise T, Mari A, DeVries JH, Urva S, Li J, Pratt EJ, Coskun T, Thomas MK, Mather KJ, Haupt A, et al

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PKCDRS, and PKC-DRS 2 Study Groups