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We discuss the use of glucagon-like peptide-1 (GLP-1) analogues as monotherapy and unimolecular dual or triple agonists that exploit the GLP-1 receptor and/or the gastric inhibitory peptide (GIP) receptor and/or the glucagon receptor

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I know the sinking feeling of hopelessness that I feel as a physician when I see yet another a severely obese patient with profound edema (often to the groin), and non-healing wounds.