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Semaglutide is a GLP-1 receptor agonist and one of the most extensively researched compounds in the weight loss and metabolic space

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However, the rapid loss of weight achieved with these medications often comes at a significant cost: considerable lean muscle ma

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Having demonstrated short-term weight loss with liraglutide in this group of obese adults, we now evaluate safety/tolerability (primary outcome) and long-term efficacy for sustaining weight loss (secondary outcome) over 2 years