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At week 52, both dulaglutide doses produced superior glycaemic control to sitagliptin, with mean HbA 1c reductions of 1.1% and 0.87% versus 0.39%, respectively (p.0.001 for both comparisons)

It slows gastric emptying, increases feelings of fullness, and enhances insulin secretion, all of which contribute to reduced calorie intake and improved glycemic control 3
doi: 10.1172/JCI81335

Continuing treatment produces additional loss for most people, though the rate continues gradually declining
The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease

Metformin Metformin is a first-line oral medication for type 2 diabetes with a long history of data supporting its use