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A mechanistic rationale for incretin-based therapeutics in the management of obesity

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Clinicians should recognize that while GLP-1 receptor agonists effectively reduce visceral fat, they represent one component of comprehensive metabolic disease management

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doi: 10.1111/dom.14110 [DOI] [PMC free article] [PubMed] [Google Scholar] 27.Willard FS, Douros JD, Gabe MB, et al

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Int J Epidemiol 44:82736

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Symptoms include: Diarrhea (typically watery but not bloody) Low-grade fever Nausea Occasional muscle aches or headache Stomach cramps and pain Vomiting The vomiting and diarrhea are the largest concerns, as patients can quickly become dehydrated

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Weight loss medications affect digestion, blood sugar, hydration, kidney function, gallbladder risk, and overall metabolism

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