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33 These observational findings align with realworld adherence to other glucoselowering medications

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For patients who have stalled out or where GLPs havent been as effective, phenome testing can help identify other causes and create different treatment algorithms, says Dr

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Prevents Type 2 Diabetes Progression By improving insulin sensitivity and beta-cell function Supports Cardiovascular Health Reduces blood pressure, LDL cholesterol, and inflammation Lowers Risk of Fatty Liver Disease (NAFLD/NASH) Helps reduce liver fat accumulation Improves PCOS Symptoms Regulates ovulation, insulin resistance, and weight in women with PCOS May Benefit Neuroprotection Early studies suggest a role in reducing neuroinflammation and cognitive decline Contraindications These GLP-1s are generally well-tolerated, but some patients should not take them

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GLP-1 receptors (GLP-1Rs) are found in both the periphery and the central nervous system (CNS), and GLP-1 binding elicits diverse physiological and behavioral effects depending on the site of action (Hayes et al., 2014)

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When Symptoms May Be Serious Get medical help right away if you have nonstop vomiting, cannot keep food or water down, or are losing weight for no clear reason

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Bydureon (exenatide extended-release) offered the convenience of weekly dosing and more even drug levels (blunting the peaks that cause nausea)

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