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Introduce drugs sequentially

Semaglutide 2.4 mg once weekly may not work well for certain populations, and the weight loss from bariatric surgery varies greatly (32% of patients with T2DM achieve 5% weight loss with semaglutide 2.4 mg) [112]
Wegovy Semaglutide Wegovy (Semaglutide) is an injectable medicine for weight loss that helps reduce appetite and increase feelings of fullness for chronic weight management

Cant et al

The most prevalent side effect of Exenatide is nausea, which may explain its weight loss effects [227]
