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In clinical trials, the typical person lost about 15% of their total body weight while taking semaglutide, and about 12% more weight than people who didnt take the medication

doi: 10.3389/fmed.2023.1089099 33 SteenholdtCDige OvesenPBrynskovJSeidelinJB

Older adults with obesity are more likely to have impaired mobility, which could be made worse by loss of muscle

All patients received medical, surgical, psychiatric, and nutritional evaluation and counseling

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GLP-1 receptor agonists enhance glucose-dependent insulin secretion from pancreatic beta cells, suppress inappropriate glucagon release, slow gastric emptying, and reduce appetite through central nervous system pathways