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The main suppliers are pharmaceutical companies, which are subject to stringent regulations and competition

The confirmatory secondary endpoint was the change in body weight from baseline to end of treatment (30 or 56 weeks)
Although the weight loss is considered clinically significant according to the clinical expert consulted by CADTH on this review, there is no clear evidence that this weight loss reduces the number of patients who may develop various weight-related comorbidities, including type 2 diabetes, cardiovascular disease, and osteoarthritis

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Low oxygen levels When the body has a low oxygen level, it goes into fight or flight mode, resulting in sweating

While the causal relationship between MASH and cardiovascular disease continues to be studied, clinical guidelines have established cardiovascular risk reduction as one of the pillars of comprehensive MASLD management
