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48% of Gen Z, 38% of all Americans)

Cell (1977) 11(4):9417.10.1016/0092-8674(77)90305-1 126 HotamisligilGS

This happens because fat is lost from the face, particularly in the cheeks, which can age your appearance
Yet the real-world data tells a different story

Dietary Gut Microbial Metabolites, Short-chain Fatty Acids, and Host Metabolic Regulation

These include certain antipsychotics (olanzapine, clozapine), mood stabilizers (valproate, lithium), antidepressants (mirtazapine, paroxetine), corticosteroids, and some diabetes medications like insulin or sulfonylureas
