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A clinical trial that just began dosing patients at Johns Hopkins is testing something the diabetes world has suspected for years: that the same class of drugs millions of people take to manage blood sugar may be quietly protecting the brain from shrinking

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The weight loss resulting from semaglutide is far more than weve seen before, says Mellor, and seems to be enough to reduce the risk of developing T2DM in addition to its action of helping to manage glucose levels

Fun fact: The B3 GEL System received FDA approval in Q2 2025 and will be launching with surgeon-led clinical investigations to build robust, evidence-based validation

Among these initially healthy women, they found that increasing baseline Lp(a) levels were associated with an increased long-term risk of major cardiovascular events