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If adverse effects outweigh benefits, discontinuation should be considered
[DOI] [PubMed] [Google Scholar] 130.Barale C., Buracco S., Cavalot F., Frascaroli C., Guerrasio A., Russo I

Some users report joint discomfort during significant weight loss phases, likely related to the mechanical and structural adaptations required as load-bearing changes

However, existing evidence remains inconsistent and, at times, contradictory 54
to mitigate side effects while approaching the relevant dosage for managing diabetes symptoms and enhancing weight loss, respectively

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