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When ceramide levels become depleted, the barrier develops tiny gaps that allow water to escape more easily

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Ryan AT, Feinle-Bisset C, Kallas A, Wishart JM, Clifton PM, Horowitz M et al

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Questions that may warrant careful consideration include: What evidence supports the prescribing decision

Selective COX-2 Inhibitors: Agents like Celecoxib and Etoricoxib target only COX-2, aiming for potent anti-inflammatory effects with a reduced risk of gastric injury
