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Description
In the Phase 2 obesity trial published in NEJM in 2023, retatrutide at the 12 mg weekly dose produced a mean placebo-adjusted body weight reduction of 22.1 percentage points (22.1% (24.2% arm) mean absolute reduction on the retatrutide arm) at 48 weeks (Jastreboff et al., NEJM, 2023)

Prati-Donaduzzi, which is also developing the medicine in partnership with a foreign company, has not yet filed for regulatory approval

Its gonna be a big part of the weight loss category going forward, Hims Chief Executive Officer Andrew Dudum said in an interview

By slowing stomach emptying and communicating with the brain to signal fullness, semaglutide naturally curbs food intake
Some patients also report less side effects
Here's how individuals using GLP-1 medications describe the misunderstandings they face and the truths they wish others knew about their weight-loss journeys: Methodology We surveyed 500 individuals taking GLP-1 medications for weight loss to explore their experiences and progress
