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In a pilot trial evaluating 104 amnestic MCI and early-stage AD patients, 20 IU and 40 IU doses of intranasal insulin improved Alzheimers Disease Assessment Scale-Cognitive subscale (ADAS-Cog 12) scores compared to placebo-treated patients, with improvements in delayed recall observed 2 months following cessation of treatment in the 20 IU group

Reduced osteoblast activity and increased adipocyte proliferation are key contributors to osteoporosis pathogenesis (Huang et al., 2020)

In this large real-world study, we were able to show durable reductions in HbA1c and body weight with emphasis on drug adherence

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