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For example, MEDI0382, one GLP-1/glucagon co-agonist developed by MedImmune, was reported to have glucose-lowering efficacy comparable to liraglutide and led to greater weight loss in mice [224]

These results, presented in 2024, provided the first solid evidence that GLP-1 drugs could meaningfully slow Alzheimers in humans

Erectile dysfunction has, however, been established as a prominent complication in the relevant demographic, affecting almost 50% of men with Type 2 diabetes across their lifetime

[DOI] [PubMed] [Google Scholar] 78.Seino S, Shibasaki T, Minami K (2011) Dynamics of insulin secretion and the clinical implications for obesity and diabetes

I think of this as more of a relief than a burden, Salas-Whalen says

This GLP-1 treatment only targets one receptor