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94 Also, ruling out existing contraindications like diabetic retinopathy and medullary thyroid cancer is necessary

This synergistic combination is why it outperformed earlier GLP-1 monotherapies like semaglutide

This receptor increases insulin secretion post-prandially, depending on glucose levels

Clinical evidence shows that most people regain significant weight within months of stopping these drugsresearch suggests 50% of lost weight returns within one yearmaking a structured approach to tapering essential rather than abrupt cessation

References Sandoval and DAlessio (2015)

Introduction to GLP-1RAs GLP-1RAs are a class of drugs that mimic the action of the GLP-1 hormone, which plays a role in regulating appetite and blood sugar levels in the body