glp 1 drug made by eli lilly Lilly's Double-Beat Widens the GLP-1 Gap—And a New Pill Could Make It Permanent Eli Lilly Gets Speedy FDA

3,4 These incretins are rapidly inactivated by DPP-4, an enzyme expressed throughout the vascular endothelial cells, venous capillary beds, gut, liver, lungs, and kidneys

It could aid individuals with obesity or associated health issues

doi: 10.1002/oby.24336

A secondary analysis of clinical trial data found that up to 40% of weight lost on semaglutide can be lean mass -- muscle and bone -- rather than fat, particularly in women and older adults

Nature Rev Disease Primers

In addition, liraglutide has been shown to decrease monocyte chemoattractant protein 1 (MCP-1), a chemokine capable of recruiting monocytes into vascular tissue leading to vascular endothelial injury, oxidative stress, and inflammatory cytokines