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Studies show that long-term calorie restriction similar to dieting or simply eating less on semaglutide lowers your core body temperature as your metabolism adapts to the reduced food intake

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The clinical advantage is faster personalization: your clinician can adjust your compounded dose in smaller increments between standard intervals, or hold you at a specific dose longer if you're experiencing significant weight loss and minimal side effects

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This does not mean oral tirzepatide does not work