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Description
the endocytic adaptor Epsin binds to the ubiquitinated intracellular domain, and the resulting Clathrin-mediated endocytosis exerts a pulling force that exposes the cleavage site in the NRR [[4][4][6][5]]
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Serena Williams was one of the many celebrities featured in a Super Bowl ad, but she may have received the most backlash.

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