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By addressing both conditions, GLP1 therapy obesity treatments provide a more holistic strategy for chronic disease care

By alleviating lipotoxicity and inflammatory signaling, dual GLP-1 receptor agonists disrupt the feed-forward cycle driving hepatic fibrosis, thus offering a therapeutic avenue to prevent or reverse liver fibrosis in MASLD (40, 48)
Moreover, in the SURPASS-4 trial, subjects at high cardiovascular risk, including (but not limited to) those with coronary artery disease, cerebrovascular disease, or congestive heart failure, were assessed for the occurrence of MACE

*Correspondence: Anton Luger, [email protected] This article was submitted to Pituitary Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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