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Background Glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) are a class of medications initially developed to treat type 2 diabetes (T2D) and obesity

Consistent with the nuclear action of Lani, most proteins downregulated by GLP-1GIPLani (cluster 1) were associated with nuclear processes such as RNA processing, neurotransmitter receptor internalization and chromosome organization, whereas proteins upregulated by GLP-1GIPLani were mainly linked to neurotransmitter receptor internalization (Fig

A recent systematic review and meta-analysis of randomized controlled trials failed to demonstrate any beneficial effects of second-generation antidepressants on cognition and depression, including various informative subgroups (Qin et al., 2022)

SGLT-2is are lipid soluble drugs with low molecular weight, as indicated by their chemical structures (Figure 3)

GLP-1 Probiotic effectively nurtures a healthy, diverse microbiome without any harmful chemicals or drugs in its formulation

2025 Jul 1;15(1):22038