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Drinking plain water is essential, but adding electrolytes can help maintain your energy levels during the 48-hour peak

This dual action makes maintaining a healthy diet more manageable and sustainable

Gastrointestinal symptoms such as nausea, vomiting, diarrhea, constipation, and abdominal discomfort are dose-dependent and usually improve with slow titration

Circulation 2022;146:18821894

People taking metformin for blood sugar management, which is known to reduce B12 absorption over time

PlexusDx patients who follow a slow titration schedule and apply dietary modifications usually progress through the symptomatic phase with minimal impact on daily life