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Common side effects include: Nausea and vomiting, especially at the start of treatment Gastrointestinal discomfort, such as bloating, diarrhea, or constipation Injection site reactions like redness, swelling, or itching Loss of lean muscle mass along with fat loss Dysesthesia, which includes tingling and skin sensitivity, is reported in as many as 20.9% of patients on higher doses
Particularly, the application of celastrol during advanced stages of adipocyte differentiation has been observed to curtail fat storage in human adipose-derived stem cells (hADSCs) by suppressing critical genes implicated in adipogenesis [50]
However, with a little preparation, you can keep your treatment on track
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