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While GLP-1 degradation is unaffected by kidney function, the clearance of both GLP-1, and to a greater extent its inactive metabolites, is delayed in patients with renal insufficiency [184]

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The results of a Phase II clinical trial have demonstrated significant weight reduction in overweight and obese adults

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The present study aims to investigate comparative dementia risk with initiators of GLP1 receptor agonists, SGLT2 inhibitors, or DPP4 inhibitors in people with type 2 diabetes aged 60 years, using real-world observational data from primary care practice records in the UK

For many women in midlife, menopause brings a host of unwanted physical changes, including weight gain and more abdominal fat