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As with all incretin-based therapies, tirzepatide carries certain safety considerations, including a potential association with pancreatitis that warrants careful clinical attention

10.1001/jama.2018.3024 Summary Keywords semaglutide, tirzepatide, dulaglutide, liraglutide, GLP-1 (Glucagon-Like Peptide 1), HbA1c, type 2 diabetes mellitus, randomized controlled trials Citation Karimi MA, Gholami Chahkand MS, Dadkhah PA, Sheikhzadeh F, Yaghoubi S, Esmaeilpour Moallem F, Deyhimi MS, Arab Bafrani M, Shahrokhi M and Nasrollahizadeh A (2025) Comparative effectiveness of semaglutide versus liraglutide, dulaglutide or tirzepatide: a systematic review and meta-analysis

According to data from CITIC Pharmaceutical, the current penetration rate in the domestic market is only 1%, while that in the US market is as high as 10%