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Protein-and calcium-mediated GLP-1 secretion: a narrative review

Protein also provides greater satiety per calorie than carbohydrates or fats (which typically have a thermic effect of 5-10% and 0-3%, respectively), which can be beneficial when appetite is already suppressed

60 In a functional human beta-cell line, it demonstrated a dose-dependent increase in insulin secretion

Rather than treating addiction as an isolated brain disorder, NRIs research recognizes it as a whole-body condition shaped by endocrine, immune, and metabolic dynamics

Front Pharmacol (2021) 12:781856

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