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New or worsening nephropathy, defined as persistent macroalbuminuria, persistent doubling of the serum creatinine level, and a creatinine clearance of 30 ml/min/1.73 m 2 should receive metformin and SGLT2i (Fig
Neuroprotective role of GLP-1 analog for retinal ganglion cells via PINK1/Parkin-Mediated mitophagy in diabetic retinopathy

Furthermore, it is well-established that glia have a substantial function in the inflammatory response of the central nervous system and thus are highly implicated in neurodegenerative diseases

Starting tirzepatide involves a managed approach, beginning after the washout period

Poeran et al.s study showed that through multivariable models, preoperative use of GLP-1 RA use was not significantly associated with increased odds of aspiration (OR 1.08
