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Adding long alkane chains makes these drugs more sticky than ordinary peptide/protein drugs, making it extremely easy to cause adsorption and residue in the LC-MS/MS system

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It is not, however, FDA-approved as an anti-inflammatory medication the anti-inflammatory effects are a documented benefit, not its primary indication

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However, it is challenging to conclude a direct benefit of HMB for body composition changes since it was combined with other ingredients [63]