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This case underscores the potential for tirzepatide to cause severe gastrointestinal dysmotility and fecal stasis, highlighting the importance of vigilance for bowel complications in patients on GLP-1 RAs who present with acute abdominal symptoms [15]

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For instance, identification of suicidal outcomes by means of ICD codes registered during routine clinical practice databases has been associated with a slight under-registration of cases, which may result in underestimation of the association between drug exposure and SIS outcomes [35], and studies validating suicidal classification have concluded that ICD codes have good positive predictive value but low specificity [36]

The drugs also come with side effects like nausea, vomiting, diarrhea and constipation