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The kidney composite reduction is consistent across CKD severity strata

The review further distinguishes between established outcome benefits (CVD, CKD, and OSA) and conditions still under investigation (neurodegeneration, arthritis, and some liver endpoints)

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(2024) Glucagon-like Peptide-1 (GLP-1) Agonists Drug Chapters The drug chapter segment of the GLP-1 agonists drug market report encloses a detailed analysis of marketed therapies and late-stage (Phase III and Phase II) therapies

results are aligned with ours revealing that BMI reductions that were seen (1.147 kg/m 2 at 24 months) indicate that GLP-1 RA weight loss effects contribute to therapeutic advantages by reducing intracranial venous pressure and decreasing the generation of pro-inflammatory adipokines

This is identical to how blood pressure medications work: they control the disease as long as you take them