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Retatrutide decreased mean SBP by up to 12.1 mmHg in persons with overweight/obesity not having uncontrolled hypertension [50], improving on results reported for tirzepatide [51] and semaglutide [52]

Although immunohistochemical investigation could not identify GLP-1R expression as a separate prognostic factor in pancreatic ductal adenocarcinoma (PDAC) patients, Cases et al

Samples with PPIB ISH scores of 2 (noted as positive) and dapB ISH scores of 0 (noted as negative) were considered to have adequate tissue viability, and GIPR and GLP-1R mRNA ISH were evaluated

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About the review This review aims to simultaneously promote GLP-1 RA research and enhance users' understanding by synthesizing evidence from recent landmark trials, thereby providing a comprehensive picture of the potential of these drugs as more than just metabolic modulators