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WAT-derived exosomal miR-23b increased BMI and IR

Changes in plasma ( A ) AST, ( B ) ALT, and ( C ) C-reactive protein (CRP) levels

When FXR is inhibited, intestinal stem cells generate more L-cells, which produce GLP-1

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Ahn and co-workers, for instance, have prepared a series of conformationally constrained GLP-1 analogs by introducing multiple lactam bridges between Glu i and Lys i +4 to stabilize two -helices at the N- and C-terminal regions