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Patients with conditions such as depression or eating disorders may need additional considerations before starting GLP-1 therapy

It lacks the essential amino acid leucine that triggers muscle protein synthesis

Interestingly, in a retrospective study of 186 patients (56% type 1 diabetes mellitus) from the Netherlands, dyspeptic symptoms, with the exception of early satiety and abdominal pain, were unrelated to delayed gastric emptying [69]

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But the USDA reiterated that there is no regulatory standard for the term "GLP-1 Friendly." Other companies are targeting GLP-1 users but not mentioning the drugs on their labels or menus