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Human data (from a meta-analysis of 894 participants) show fenugreek supplementation (0.5 g to 10 g daily over 4 weeks to 6 months) reduces fasting glucose, post-meal glucose, and HbA1c

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FDA Approves Oral Semaglutide as a GLP-1 Pill for Weight Loss at Centra Internal Medicine

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These adaptations position irisin as a promising therapeutic target for preventing metabolic disorders and optimizing exercise protocols
