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Description
In contrast, GLP-1 RAs such as tirzepatide had ICERs approaching $197,000 per QALY in some models [8], well beyond typical WTP thresholds used in health policy evaluations
Most people achieve better results by overcoming injection anxiety rather than settling for less effective oral options

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GIP receptor activation adds a complementary layer
Real-world comparative effectiveness studies have corroborated clinical trial findings

Methods This systematic review was conducted across PubMed/MEDLINE and Web of Science
