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To minimise confounding effects, we compared GLP-1RAs with second- or third-line glucose-lowering medications

Providing a treatment option that is proven to lower this cardiovascular risk is a major advance for public health. The FDAs decision is largely based on data from the SELECT trial, which included more than 17,000 overweight or obese patients with a baseline age of 45 years old

The widespread use of these drugs, combined with the fact that cancer is a leading cause of morbidity and mortality globally, necessitates a deeper understanding of how GLP-1 signaling might influence cancer risk and survival

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doi: 10.1073/pnas.0600655103

It is estimated that, by 2022, approximately 31% of adults worldwide failed to meet the minimum recommended levels of physical activitya figure that has increased since 2000 due to rising urbanization and mechanization [31]