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Its growing sales turned out to exceed manufacturing capacity of the manufacturer, causing extreme shortages in many countries around the world

An important point patients should understand from the outset: stopping semaglutide abruptly after reaching a target weight often leads to partial weight regain

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The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms. An estimated 1.6 million UK adults used GLP-1s such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro) to lose weight between early 2024 and early 2025, with an additional 3.3 million interested in using weight loss drugs during 2026