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The medical community regards substance addiction as a chronic condition: While it can be effectively managed (with abstinence), it is likely to progress in severity without treatment

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Weight continues declining through week 48 and beyond based on Phase 3 trial data

Studies of caloric restriction consistently demonstrate that muscle tissue accounts for a meaningful portion of weight lost, even with exercise

Both medications benefit from microdosing protocols, but patients intolerant to semaglutide even with slow titration may tolerate tirzepatide better

Originally approved to help manage type 2 diabetes, it has since been approved for weight loss